Marie Mosquini (December 3, 1899 – February 21, 1983) was an American film actress.

She appeared in 202 films between 1917 and 1929. After leaving high school she became the resident ingenue at the Hal Roach studio, appearing opposite Roach's comedy stars Harold Lloyd, Snub Pollard, and Stan Laurel.

In October, 1930, Marie retired from acting and married an inventor 26 years her senior: Lee de Forest. She became his fourth and longest-lasting wife, staying with him until his death in 1961. In 1967, Marie donated her husband's papers and historic prototypes to the Perham Foundation, now held at History San Jose. In 1968, she became a Novice Class amateur radio operator; her call sign was WB6ZJR. In 1973, she participated in a radio broadcast celebrating the centennial of her husband's birth.

She was born and died in Los Angeles, California.

Selected filmography

• We Never Sleep (1917)
• All Aboard (1917)
• Love, Laughs and Lather (1917)
• From Laramie to London (1917)
• Lonesome Luke Loses Patients (1917)
• Lonesome Luke's Wild Women (1917)
• Lonesome Luke, Mechanic (1917)
• Stop! Luke! Listen! (1917)
• Lonesome Luke on Tin Can Alley (1917)
• She Loves Me Not (1918)
• That's Him (1918)
• Just Rambling Along (1918)
• No Place Like Jail (1918)
• The Tip (1918)
• From Hand to Mouth (1919)
• Captain Kidd's Kids (1919)
• His Only Father (1919)
• Pay Your Dues (1919)
• Count the Votes (1919)
• Soft Money (1919)
• He Leads, Others Follow (1919)
• The Rajah (1919)
• Be My Wife (1919)
• Don't Shove (1919)
• Heap Big Chief (1919)
• Chop Suey & Co. (1919)
• Count Your Change (1919)
• A Jazzed Honeymoon (1919)
• Just Neighbors (1919)
• Off the Trolley (1919)
• Swat the Crook (1919)
• The Marathon (1919)
• Si, Senor (1919)
• Ring Up the Curtain (1919)
• Crack Your Heels (1919)
• Young Mr. Jazz (1919)
• A Sammy In Siberia (1919)
• Look Out Below (1919)
• I'm on My Way (1919)
• Hoots Mon! (1919)
• On the Fire (1919)
• Hustling for Health (1919)
• Going! Going! Gone! (1919)
• Wanted - $5,000 (1919)
• Do You Love Your Wife? (1919)
• His Royal Slyness (1920)
• It's a Gift (1923)
• Save the Ship (1923)
• Short Orders (1923)
• Good and Naughty (1926)
• 7th Heaven (1927)
• The Black Book (1929)