Stefano Cipriani was born into a large family of 13 children in Rome and spent his childhood and youth at e fourth floor, door Via Eustacchio Manfredi 17, on number 16. The yellow house where he lived in his childhood is not far from Villa Glori in the Paroli neighbourhood. Some of his brothers and sisters are: Lucia Nadia Cipriani, Giovanni Cipriani, Armando Cipriani, Luigi Cipriani, Massimo Cipriani, Silvio Cipriani, Teresa Maria Cipriani, Letizia Cipriani, Liliana Cipriani.

His mother's name was Gabriella Cipriani - Merolli. His mother died of cervical cancer. His father was Vincenzo Cipriani. His father had an upholstery business and was self-employed.