The tower controllers on duty that day at National testified that the P-38 had taken off on Runway 3, turned left north of The Pentagon, circled over Arlington, then returned, requesting permission to land due to engine trouble. The controller cleared the aircraft to join the left traffic pattern, but instead it flew south of the airport and entered a long straight-in approach at the same time Flight 537 was turning onto a shorter final. The controller then called Flight 537 ordering it to turn left; it began the turn, but by then the P-38, being considerably faster than a DC-4 on final, overtook the aircraft 1/2 mile southwest of the threshold of Runway 3.

The DC-4 was cut in half by the left propeller of the P-38 just forward of the trailing edge of the wing. The aft portion of the DC-4 fell to the ground on the west bank of the Potomac River; other pieces were located in Alexandria, Virginia at the Richmond, Fredericksburg & Potomac Railroad Potomac Yard and on a highway passing near the Yard. The fore portion of the aircraft fell into the river, as did the P-38.

"Many hours following the collision of an Eastern Air Lines passenger transport and a Bolivian fighter plane, the search went on today under the glare of floodlights for the nine passengers whose bodies had not yet been recovered.

"Shocked Members of Congress, stunned by the loss of one of their own number (Dem. George J. Bates), promised a complete air safety investigation. The Civil Aeronautics Board said its hearings into the cause of the crash will start in a few days. The airline scheduled a probe of its own, as well. The disaster occurred as the big DC-4 transport headed into the National Airport for a landing shortly before noon, flying at about 300 feet.

"Into the traffic pattern, calling for landing instructions, came a P-38 fighter piloted by Bolivia's top airman, Erick Rios Bridoux. Bridoux was testing the twin-engine craft which his government had purchased from the United States. An airport tower operator a bare half-mile away saw the P-38 bear down on the transport. He cried a radio warning to the 28-year-old Bolivian, but the P-38 kept coming. Then the tower frantically signalled the transport. The DC-4 pilot swerved the big ship from its path, but too late. The fighter ripped into it from above and from the side. The airliner split in half. Bodies and wreckage fell into the water and along the bank of the Potomac."

Air Force Sergeant Morris J. Flounlacker hauled the weakly treading Bridoux out of the Potomac, just as the wounded pilot lost consciousness. At Alexandria Hospital doctors found he had a broken back, crushed ribs and serious contusions.

Bridoux contradicted much of the tower controllers' testimony when he spoke to Civil Aeronautics Board (CAB) investigators. He claimed he had taken off from Runway 36, had been in constant contact with the tower, and had been explicitly cleared to land on Runway 3 under the call sign "Bolivian 927". However, the testimony of both the tower personnel and a military controller listening in on the frequency from his position at Bolling Air Force Base (as well as other discrepancies in the P-38 pilot's testimony) led the CAB to discount Bridoux's version of the facts. As Bridoux spoke and understood English well, it was thought that language difficulties played no part in the accident.

The CAB determined the primary probable causes of the accident to be the P-38 pilot's decision to land without proper clearance and his failure to exercise normal vigilance in looking out for conflicting traffic. The CAB also found that the tower controllers failed to exercise due vigilance in not notifying the pilots of Flight 537 earlier as to the critical traffic situation developing. However, the report also states that even if Flight 537 had received earlier advice with respect to the P-38's location, it might still have been too late to avoid the accident, as Bridoux's actions left Flight 537 only a few seconds in which to turn.

Among the dead on Flight 537 were Congressman George J. Bates, New Yorker cartoonist Helen E. Hokinson, and former Congressman Michael J. Kennedy.